Vascular endothelial growth factor production in polymyalgia rheumatica
نویسندگان
چکیده
منابع مشابه
Vascular Endothelial Growth Factor Production is Regulated by Gene Polymorphisms
Background: Vascular endothelial growth factor (VEGF) has a key role in angiogene-sis and in transplantation. The level of VEGF is related to the differences in the DNA sequence of its promoter region. Objectives: In this study, the association between the combination of VEGF –1154 G and –2578 C alleles and VEGF production by LPS-stimulated PBMCs was investigated. In addition; the relationship ...
متن کاملScintigraphic Findings and Serum Matrix Metalloproteinase 3 and Vascular Endothelial Growth Factor Levels in Patients with Polymyalgia Rheumatica
Objective: Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease that affects elderly people and is associated with synovitis. Recently, matrix metalloproteinase 3 (MMP 3) and vascular endothelial growth factor (VEGF) were reported to be involved in the pathogenesis of PMR-related synovitis. New evidence regarding the pathogenesis of PMR has been found; however, the diagnosis and ou...
متن کاملArticular and vascular manifestations of polymyalgia rheumatica.
Polymyalgia rheumatica is a syndrome encountered by no means infrequently in middle-aged and elderly people. It is characterized by pains and stiffness, which are more severe in the morning, are felt to be in the shoulder and hip girdle muscles and often in the spine and are usually associated with fatigue, malaise, anorexia, loss of weight, and depression. The most constant laboratory finding ...
متن کاملVascular Endothelial Growth Factor from Embryonic Status to Cardiovascular Pathology
Vascular endothelial growth factor (VEGF) is a multifunctional cytokine with distinct functions in angiogenesis, lymphangiogenesis, vascular permeability, and hematopoiesis. VEGF is a highly conserved, disulfide-bonded dimeric glycoprotein of 34 to 45 kDa produced by several cell types including fibroblasts, neutrophils, endothelial cells, and peripheral blood mononuclear cells, particularly T ...
متن کاملvascular endothelial growth factor production is regulated by gene polymorphisms
background: vascular endothelial growth factor (vegf) has a key role in angiogene-sis and in transplantation. the level of vegf is related to the differences in the dna sequence of its promoter region. objectives: in this study, the association between the combination of vegf –1154 g and –2578 c alleles and vegf production by lps-stimulated pbmcs was investigated. in addition; the relationship ...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2000
ISSN: 0004-3591,1529-0131
DOI: 10.1002/1529-0131(200011)43:11<2472::aid-anr14>3.0.co;2-b